منابع مشابه
Is bigger better?
What is medical science all about? Surely it is about the value chain, which begins with basic research and ends—if there is an end— with a useful product. There is a widespread perception that scientists do a lot of basic research, but neglect the application of their findings. To remedy this, a number of organizations and philanthropists have become dedicated advocates of applied or translati...
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We develop a model in which the value of a firm’s reputation for quality increases gradually over time. In our model, a firm’s ability to deliver high quality at any given period depends on how much it invests in quality. This investment is the firm’s private information. Also, a firm’s current quality is unobservable. Thus the only observable is a firm’s past performance the realized quality o...
متن کاملCommentary YAC transgenes : Bigger is probably better
A number of recent articles have reported the successful generation of transgenic mouse lines carrying large fragments of DNA contained in yeast artificial chromosomes (YACs) (1-5). The ability to transfer such large segments of DNA provides a number of opportunities, including the analysis ofthe function of large genes or gene clusters in their natural DNA configuration, the study of the influ...
متن کامل802.11 Buffers: When Bigger Is Not Better?
While there have been considerable advances in the modelling of 802.11’s MAC layer in recent years, 802.11 with finite buffer space is considered difficult to analyse. In this paper, we study the impact of finite buffers’ effect on the 802.11 performance, in view of the requirements of interactive applications sensitive to delay and packet loss. Using both state-of-the art and simplified queuei...
متن کاملCoronary artery disease genetics: bigger is better.
The complexity of coronary artery disease genetics arises from the diversity of clinical phenotypes and from the many biological pathways that contribute to atherosclerotic plaque biology, including lipid metabolism, inflammation, endothelial function, oxidative stress and thrombosis. In addition to environmental factors, interindividual variation in disease susceptibility or outcome may arise ...
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ژورنال
عنوان ژورنال: Acta Neurochirurgica
سال: 2011
ISSN: 0001-6268,0942-0940
DOI: 10.1007/s00701-011-1030-5